L-Arginine-Derived Polyamidoamine Oligomers Bearing at Both Ends β-Cyclodextrin Units as pH-Sensitive Curcumin Carriers

L-Arginine-Derived Polyamidoamine Oligomers Bearing at Both Ends β-Cyclodextrin Units as pH-Sensitive Curcumin Carriers

The aza-Michael polyaddition of L-arginine and <i>N</i>,<i>N</i>′-methylene-bis-acrylamide gives the biocompatible and easily cell-internalized polyamidoamine ARGO7. By controlled synthesis, two ARGO7 oligomers, namely a trimer and a pentamer, bearing acrylamide terminal unit...

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Bibliographic Details
Main Authors: Sofia Treccani, Jenny Alongi, Amedea Manfredi, Paolo Ferruti, Roberta Cavalli, Giuseppina Raffaini, Elisabetta Ranucci
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Polymers
Subjects:
β-cyclodextrin
polyamidoamines
curcumin
drug release
molecular modeling
Online Access:https://www.mdpi.com/2073-4360/14/15/3193

Internet

https://www.mdpi.com/2073-4360/14/15/3193

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