A human <it>MYBPC3</it> mutation appearing about 10 centuries ago results in a hypertrophic cardiomyopathy with delayed onset, moderate evolution but with a risk of sudden death

A human <it>MYBPC3</it> mutation appearing about 10 centuries ago results in a hypertrophic cardiomyopathy with delayed onset, moderate evolution but with a risk of sudden death

<p>Abstract</p> <p>Background</p> <p>Hypertrophic Cardiomyopathy (HCM) is a genetically heterogeneous disease. One specific mutation in the <it>MYBPC3</it> gene is highly prevalent in center east of France giving an opportunity to define the clinical profile...

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Bibliographic Details
Main Authors: Teirlinck Carolien H, Senni Faïza, Malti Rajae El, Majoor-Krakauer Danielle, Fellmann Florence, Millat Gilles, André-Fouët Xavier, Pernot François, Stumpf Michaël, Boutarin Jean, Bouvagnet Patrice
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Medical Genetics
Subjects:
Hypertrophic cardiomyopathy
MYBPC3
Mutation
Founder effect
Online Access:http://www.biomedcentral.com/1471-2350/13/105

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http://www.biomedcentral.com/1471-2350/13/105

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