VAL158MET catechol O-methyltransferase polymorphism contributes to the development of preeclampsia

Objectives: Establishment of association between: (a) Val158Met COMT (G1947A) polymorphism and preeclampsia; (b) cytokines gene expression and COMT genotypes. Methods: 50 preeclampsia and 50 healthy pregnant women were enrolled. COMT genotyping was done by PCR/RFLP. TNF-α, IL-1β, and IL-6 mRNA level...

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Bibliographic Details
Main Authors: Tamara Sljivancanin Jakovljevic, Olivera Kontic-Vucinic, Nadja Nikolic, Jelena Carkic, Jelena Milasin
Format: Article
Language:English
Published: Taylor & Francis Group 2020-10-01
Series:Hypertension in Pregnancy
Subjects:
Online Access:http://dx.doi.org/10.1080/10641955.2020.1843663