Regulatory T Cells Suppress Inflammation and Blistering in Pemphigoid Diseases

Regulatory T Cells Suppress Inflammation and Blistering in Pemphigoid Diseases

Regulatory T cells (Tregs) are well known for their modulatory functions in adaptive immunity. Through regulation of T cell functions, Tregs have also been demonstrated to indirectly curb myeloid cell-driven inflammation. However, direct effects of Tregs on myeloid cell functions are insufficiently...

Full description

Bibliographic Details
Main Authors: Katja Bieber, Shijie Sun, Mareike Witte, Anika Kasprick, Foteini Beltsiou, Martina Behnen, Tamás Laskay, Franziska S. Schulze, Elena Pipi, Niklas Reichhelm, René Pagel, Detlef Zillikens, Enno Schmidt, Tim Sparwasser, Kathrin Kalies, Ralf J. Ludwig
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
regulatory T cells
autoimmunity
skin
pemphigoid disease
neutrophil activation
Th1
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01628/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01628/full

Similar Items