Soluble interleukin-1 receptor type 2 plasma levels in Parkinson’s disease: relationship with cardiac autonomic profile before and after peripheral mechanical somatosensory stimulation

Introduction: Systemic inflammation promotes neurodegeneration in Parkinson’s disease (PD). Interleukin-1 receptor type 2 (sIL-1R2) plasma levels increase during inflammation. Data on sIL-1R2 in PD patients and its relationship with PD cardiac autonomic profile are limited, given the possible anti-i...

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Bibliographic Details
Main Authors: Dana Shiffer, Antonio Roberto Zamunér, Maura Minonzio, Mara Bulgheroni, Alberto Porta, Roberto Leone, Barbara Bottazzi, Cecilia Garlanda, Francesco Colotta, Franca Barbic, Alberto Mantovani, Raffaello Furlan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1168652/full