Modification of mesenchymal stem cells for cartilage-targeted therapy

Abstract Osteoarthritis (OA) is a chronic degenerative joint disease characterized by the destruction of the articular cartilage, sclerosis of the subchondral bone, and joint dysfunction. Its pathogenesis is attributed to direct damage and mechanical destruction of joint tissues. Mesenchymal stem ce...

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Bibliographic Details
Main Authors: Jianghong Huang, Qisong Liu, Jiang Xia, Xi Chen, Jianyi Xiong, Lei Yang, Yujie Liang
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-022-03726-8