Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes
Trained immunity refers to the long-lasting memory traits of innate immunity. Recent studies have shown that trained immunity is orchestrated by sustained changes in epigenetic marks and metabolic pathways, leading to an altered transcriptional response to a second challenge. However, the potential...
| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Article |
| Langue: | English |
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American Society for Clinical Investigation
2022-04-01
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| Collection: | The Journal of Clinical Investigation |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1172/JCI147719 |