Melatonin inhibits HCC progression through regulating the alternative splicing of NEMO

Melatonin inhibits HCC progression through regulating the alternative splicing of NEMO

Hepatocellular carcinoma (HCC) is one of the most common primary cancers with limited therapeutic options. Melatonin, a neuroendocrine hormone produced primarily by the pineal gland, demonstrates an anti-cancer effect on a myriad of cancers including HCC. However, whether melatonin could suppress tu...

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Bibliographic Details
Main Authors: Lu Bai, Siwen Sun, Wenmei Su, Chaoqun Chen, Yuesheng Lv, Jinrui Zhang, Jinyao Zhao, Man Li, Yangfan Qi, Wenjing Zhang, Yang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
melatonin
HCC
NEMO
alternative splicing
MT1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1007006/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1007006/full

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