The Effects of Topiroxostat, a Selective Xanthine Oxidoreductase Inhibitor, on Arterial Stiffness in Hyperuricemic Patients with Liver Dysfunction: A Sub-Analysis of the BEYOND-UA Study

The Effects of Topiroxostat, a Selective Xanthine Oxidoreductase Inhibitor, on Arterial Stiffness in Hyperuricemic Patients with Liver Dysfunction: A Sub-Analysis of the BEYOND-UA Study

Background: The effects of uric acid (UA)-lowering therapy with xanthine oxidoreductase (XOR) inhibitors on the development of cardiovascular diseases remain controversial. Based on recent findings that plasma XOR activity increased in liver disease conditions, we conducted a sub-analysis of the BEY...

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Bibliographic Details
Main Authors: Yuya Fujishima, Hitoshi Nishizawa, Yusuke Kawachi, Takashi Nakamura, Seigo Akari, Yoshiyuki Ono, Shiro Fukuda, Shunbun Kita, Norikazu Maeda, Satoshi Hoshide, Iichiro Shimomura, Kazuomi Kario
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
hyperuricemia
hypertension
arterial stiffness
xanthine oxidoreductase inhibitors
liver dysfunction
Online Access:https://www.mdpi.com/2227-9059/11/3/674

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https://www.mdpi.com/2227-9059/11/3/674

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