The mechanism of dendritic cell-T cell crosstalk in rheumatoid arthritis

The mechanism of dendritic cell-T cell crosstalk in rheumatoid arthritis

Abstract Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by joint pain and swelling, synovial hyperplasia, cartilage damage, and bone destruction. The mechanisms of dendritic cell (DC) and T cell-mediated crosstalk have gradually become a focus of attention. DCs regulate th...

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Bibliographic Details
Main Authors: Zhandong Wang, Jinlong Zhang, Fangyu An, Jie Zhang, Xiangrui Meng, Shiqing Liu, Ruoliu Xia, Gang Wang, Chunlu Yan
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Dendritic cells
Chemokines
PD-L1/PD-1 signalling axis
TGF-β signalling axis
Crosstalk mechanism
Online Access:https://doi.org/10.1186/s13075-023-03159-8

Internet

https://doi.org/10.1186/s13075-023-03159-8

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