Intracellular eukaryotic parasites have a distinct unfolded protein response.

Intracellular eukaryotic parasites have a distinct unfolded protein response.

Insult to the endoplasmic reticulum (ER) activates the Unfolded Protein Response (UPR), a set of signaling pathways that protect the cell from the potential damage caused by improperly folded proteins. Accumulation of misfolded proteins in the ER lumen initiates a series of signal transduction event...

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Bibliographic Details
Main Authors: Sara J C Gosline, Mirna Nascimento, Laura-Isobel McCall, Dan Zilberstein, David Y Thomas, Greg Matlashewski, Michael Hallett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084755?pdf=render

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http://europepmc.org/articles/PMC3084755?pdf=render

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