Brief Report: Acetaminophen Reduces Neoadjuvant Chemoimmunotherapy Efficacy in Patients With NSCLC by Promoting Neutrophil Extracellular Trap Formation: Analysis From a Phase 2 Clinical Trial

Brief Report: Acetaminophen Reduces Neoadjuvant Chemoimmunotherapy Efficacy in Patients With NSCLC by Promoting Neutrophil Extracellular Trap Formation: Analysis From a Phase 2 Clinical Trial

Introduction: Neoadjuvant chemoimmunotherapy has recently been the standard of care for resectable locally advanced NSCLC. Factors affecting the neoadjuvant immunotherapy efficacy, however, remain elusive. Metabolites have been found to modulate immunity and associate with immunotherapeutic efficacy...

Full description

Bibliographic Details
Main Authors: Chongwu Li, MD, Junqi Wu, MD, Lei Zhang, MD, Fang Wang, MD, Long Xu, MD, Yue Zhao, MD, Yun Xiao, PhD, Fenghui Zhuang, MD, Likun Hou, MD, PhD, Deping Zhao, MD, PhD, Yunlang She, MD, PhD, Dong Xie, MD, PhD, Chang Chen, MD, PhD
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:JTO Clinical and Research Reports
Subjects:
Neoadjuvant
Immunotherapy
Lung cancer
Neutrophil extracellular traps
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364323000991

Internet

http://www.sciencedirect.com/science/article/pii/S2666364323000991

Similar Items