Concomitant Treatment with Voriconazole and Flucloxacillin: A Combination to Avoid

Concomitant Treatment with Voriconazole and Flucloxacillin: A Combination to Avoid

Background: Voriconazole is an antifungal drug used as one of the first-line treatments for invasive aspergillosis. This drug is extensively metabolized, predominantly via cytochrome P450 enzymes. An interaction between flucloxacillin and voriconazole, leading to subtherapeutic voriconazole concentr...

Full description

Bibliographic Details
Main Authors: Ruth Van Daele, Joost Wauters, Pieter De Cock, Franky Buyle, John Leys, Pieter Van Brantegem, Matthias Gijsen, Pieter Annaert, Yves Debaveye, Katrien Lagrou, Willy E. Peetermans, Roger J. Brüggemann, Isabel Spriet
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
drug–drug interaction
voriconazole
flucloxacillin
CYP450 enzymes
underexposure
Online Access:https://www.mdpi.com/2079-6382/10/9/1112

Internet

https://www.mdpi.com/2079-6382/10/9/1112

Similar Items