Novel epigenetic target therapy for prostate cancer: a preclinical study.

Epigenetic events are critical contributors to the pathogenesis of cancer, and targeting epigenetic mechanisms represents a novel strategy in anticancer therapy. Classic demethylating agents, such as 5-Aza-2'-deoxycytidine (Decitabine), hold the potential for reprograming somatic cancer cells d...

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Bibliographic Details
Main Authors: Ilaria Naldi, Monia Taranta, Lisa Gherardini, Gualtiero Pelosi, Federica Viglione, Settimio Grimaldi, Luca Pani, Caterina Cinti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4031137?pdf=render