Adult health and transition stage-specific rotenone-mediated Drosophila model of Parkinson’s disease: Impact on late-onset neurodegenerative disease models

Adult health and transition stage-specific rotenone-mediated Drosophila model of Parkinson’s disease: Impact on late-onset neurodegenerative disease models

Parkinson’s disease (PD) affects almost 1% of the population worldwide over the age of 50 years. Exposure to environmental toxins like paraquat and rotenone is a risk factor for sporadic PD which constitutes 95% of total cases. Herbicide rotenone has been shown to cause Parkinsonian symptoms in mult...

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Bibliographic Details
Main Authors: Mohamad Ayajuddin, Limamanen Phom, Zevelou Koza, Priyanka Modi, Abhik Das, Rahul Chaurasia, Abuno Thepa, Nukshimenla Jamir, Kelevikho Neikha, Sarat Chandra Yenisetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Drosophila
Parkinson’s disease
rotenone
health phase
transition phase
dopamine
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.896183/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.896183/full

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