Bidirectional two-sample mendelian randomization analysis identifies causal associations of MRI-based cortical thickness and surface area relation to NAFLD

Bidirectional two-sample mendelian randomization analysis identifies causal associations of MRI-based cortical thickness and surface area relation to NAFLD

Abstract Background Non-alcoholic fatty liver disease (NAFLD) patients have exhibited extra-hepatic neurological changes, but the causes and mechanisms remain unclear. This study investigates the causal effect of NAFLD on cortical structure through bidirectional two-sample Mendelian randomization an...

Full description

Bibliographic Details
Main Authors: Zun Mao, Zhi-xiang Gao, Tong Ji, Sheng Huan, Guo-ping Yin, Long Chen
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Lipids in Health and Disease
Subjects:
GWAS
NAFLD
Cortical structure
Brain-liver axis
Online Access:https://doi.org/10.1186/s12944-024-02043-x

Internet

https://doi.org/10.1186/s12944-024-02043-x

Similar Items