Novel Oxime Synthesized from a Natural Product of <i>Senecio nutans</i> SCh. Bip. (Asteraceae) Enhances Vascular Relaxation in Rats by an Endothelium-Independent Mechanism

Novel Oxime Synthesized from a Natural Product of <i>Senecio nutans</i> SCh. Bip. (Asteraceae) Enhances Vascular Relaxation in Rats by an Endothelium-Independent Mechanism

<i>Senecio nutans</i> Sch. Bip. and its constituents are reported to have antihypertensive effects. We isolated metabolite–1, a natural compound from <i>S. nutans</i> (4-hydroxy-3-(isopenten-2-yl)-acetophenone), and synthesized novel oxime – 1 (4-hydroxy-3-(isopenten-2-yl)-ac...

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Bibliographic Details
Main Authors: Javier Palacios, Adrián Paredes, Marcelo A. Catalán, Chukwuemeka R. Nwokocha, Fredi Cifuentes
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
natural products
oxime
vascular relaxation
endothelium
rat aorta
Online Access:https://www.mdpi.com/1420-3049/27/10/3333

Internet

https://www.mdpi.com/1420-3049/27/10/3333

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