ROCK1/MLC2 inhibition induces decay of viral mRNA in BPXV infected cells

Abstract Rho-associated coiled-coil containing protein kinase 1 (ROCK1) intracellular cell signaling pathway regulates cell morphology, polarity, and cytoskeletal remodeling. We observed the activation of ROCK1/myosin light chain (MLC2) signaling pathway in buffalopox virus (BPXV) infected Vero cell...

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Bibliographic Details
Main Authors: Ram Kumar, Yogesh Chander, Nitin Khandelwal, Assim Verma, Krishan Dutt Rawat, Brij N. Shringi, Yash Pal, Bhupendra N. Tripathi, Sanjay Barua, Naveen Kumar
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21610-9