Multiscale modeling of collective cell migration elucidates the mechanism underlying tumor–stromal interactions in different spatiotemporal scales
Abstract Metastasis is the pathogenic spread of cancer cells from a primary tumor to a secondary site which happens at the late stages of cancer. It is caused by a variety of biological, chemical, and physical processes, such as molecular interactions, intercellular communications, and tissue-level...
Main Authors: | Zarifeh Heidary, Shaghayegh Haghjooy Javanmard, Iman Izadi, Nasrin Zare, Jafar Ghaisari |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-20634-5 |
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