410 Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge and Resistance in Male Offspring to a High Fat Diet

OBJECTIVES/GOALS: Maternal undernutrition, a form of malnutrition, can alter neonatal leptin signaling and result in metabolic dysfunction in adulthood. We developed a mild undernutrition model to relate more to societys nutritional challenges and to test the hypothesis that a shift in the neonatal...

Full description

Bibliographic Details
Main Authors: Tiffany K. Miles, Melody L. Allensworth, Ana Rita Silva Moreira, Angela K. Odle, Anessa Haney, Alexandra Lagasse, Angus M. MacNicol, Gwen V. Childs
Format: Article
Language:English
Published: Cambridge University Press 2022-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866122002370/type/journal_article