Citrullination in Rheumatoid Arthritis—A Process Promoted by Neutrophil Lysis?

Anti-citrullinated protein antibodies (ACPAs) are highly specific serologic markers for rheumatoid arthritis (RA) and can pre-date clinical disease onset by up to 10 years, also predicting erosive disease. The process of citrullination, the post-translational conversion of arginine to citrulline res...

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Bibliographic Details
Main Authors: Tal Gazitt, Christian Lood, Keith B. Elkon
Format: Article
Language:English
Published: Rambam Health Care Campus 2016-10-01
Series:Rambam Maimonides Medical Journal
Subjects:
Online Access:http://rmmj.org.il/Pages/ArticleHTM.aspx?manuId=608