mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant

mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant

A longitudinal study in mice reveals that a booster dose of mRNA vaccine BNT162b2 enhances humoral and cell-mediated responses and provides sterilizing immunity against Omicron-induced lung infection in aged animals.

Bibliographic Details
Main Authors: Etsuro Nanishi, Marisa E. McGrath, Timothy R. O’Meara, Soumik Barman, Jingyou Yu, Huahua Wan, Carly A. Dillen, Manisha Menon, Hyuk-Soo Seo, Kijun Song, Andrew Z. Xu, Luke Sebastian, Byron Brook, Anna-Nicole Bosco, Francesco Borriello, Robert K. Ernst, Dan H. Barouch, Sirano Dhe-Paganon, Ofer Levy, Matthew B. Frieman, David J. Dowling
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03765-3

Internet

https://doi.org/10.1038/s42003-022-03765-3

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