Role of Masseter Muscle β2-Adrenergic Signaling in Regulation of Muscle Activity, Myosin Heavy Chain Transition, and Hypertrophy

Chronic administration of clenbuterol (CB), a lipophilic β2-adrenoceptor (β2-AR) agonist, induces skeletal muscle hypertrophy and slow-to-fast fiber–type transitions in mammalian species, but the mechanism and pathophysiological roles of these changes have not been explored. Here, we examined the ef...

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Bibliographic Details
Main Authors: Yoshiki Ohnuki, Daisuke Umeki, Wenqian Cai, Nobuhiko Kawai, Yasumasa Mototani, Kouichi Shiozawa, Hui-Ling Jin, Takayuki Fujita, Eiji Tanaka, Yasutake Saeki, Satoshi Okumura
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319302816