Pullulan: an advantageous natural polysaccharide excipient to formulate tablets of alendronate-loaded microparticles

This work reports the preparation of tablets by direct compression of sodium alendronate-loaded microparticles, using pullulan as filler. The tableting properties of pullulan were compared with those of microcrystalline cellulose and lactose. Pullulan tablets showed low variations in average weight,...

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Bibliographic Details
Main Authors: Luana Mota Ferreira, Aline de Arce Velasquez, Scheila Rezende Schaffazick, Letícia Cruz
Format: Article
Language:English
Published: Universidade de São Paulo 2015-03-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100027&lng=en&tlng=en