<em>Tm</em>Spz-like Plays a Fundamental Role in Response to <em>E. coli</em> but Not <em>S. aureus</em> or <em>C. albican</em> Infection in <em>Tenebrio molitor</em> via Regulation of Antimicrobial Peptide Production

<em>Tm</em>Spz-like Plays a Fundamental Role in Response to <em>E. coli</em> but Not <em>S. aureus</em> or <em>C. albican</em> Infection in <em>Tenebrio molitor</em> via Regulation of Antimicrobial Peptide Production

The cystine knot protein Spätzle is a Toll receptor ligand that modulates the intracellular signaling cascade involved in the nuclear factor kappa B (NF-κB)-mediated regulation of antimicrobial peptide (AMP)-encoding genes. Spätzle-mediated activation of the Toll pathway is critical for the innate i...

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Bibliographic Details
Main Authors: Ho Am Jang, Bharat Bhusan Patnaik, Maryam Ali Mohammadie Kojour, Bo Bae Kim, Young Min Bae, Ki Beom Park, Yong Seok Lee, Yong Hun Jo, Yeon Soo Han
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
Spätzle
<i>T. molitor</i>
RNA interference
antimicrobial peptide
NF-κB
innate immunity
Online Access:https://www.mdpi.com/1422-0067/22/19/10888

Internet

https://www.mdpi.com/1422-0067/22/19/10888

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