Dissecting dormancy and quiescence in hematopoietic stem cells

Quiescence is a fundamental state of adult hematopoietic stem cells (HSCs) characterized by their residence in the G0 phase of the cell cycle. Despite being quiescent, HSCs retain their capacities for self-renewal and multipotency, enabling them to produce all blood lineages. Recent discoveries have...

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Bibliographic Details
Main Authors: Liliia Ibneeva, Tatyana Grinenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Hematology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/frhem.2024.1401713/full