Sensing Lanthanide Metal Content in Biological Tissues with Magnetic Resonance Spectroscopy

The development and validation of MRI contrast agents consisting of a lanthanide chelate often requires a determination of the concentration of the agent in ex vivo tissue. We have developed a protocol that uses 70% nitric acid to completely digest tissue samples that contain Gd(III), Dy(III), Tm(II...

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Bibliographic Details
Main Authors: Mark D. Pagel, Jessica F. Li, Sandra I. Gonzalez, Dina V. Hingorani
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/13/10/13732