Sensing Lanthanide Metal Content in Biological Tissues with Magnetic Resonance Spectroscopy
The development and validation of MRI contrast agents consisting of a lanthanide chelate often requires a determination of the concentration of the agent in ex vivo tissue. We have developed a protocol that uses 70% nitric acid to completely digest tissue samples that contain Gd(III), Dy(III), Tm(II...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-10-01
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Series: | Sensors |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8220/13/10/13732 |