Influence of <it>HRH2</it> promoter polymorphism on aberrant DNA methylation of <it>DAPK</it> and <it>CDH1</it> in the gastric epithelium

Influence of <it>HRH2</it> promoter polymorphism on aberrant DNA methylation of <it>DAPK</it> and <it>CDH1</it> in the gastric epithelium

<p>Abstract</p> <p>Background</p> <p>Aberrant methylation patterns in CpG island are known to be influential in gene silencing. Histamine plays important physiological roles in the upper gastrointestinal tract and acts via the H2 receptor. We report an investigation int...

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Bibliographic Details
Main Authors: Nomura Tomoe, Tahara Tomomitsu, Shiroeda Hisakazu, Minato Takahiro, Matsue Yasuhiro, Hayashi Ranji, Matsunaga Kazuhiro, Otsuka Toshimi, Nakamura Masakatsu, Toshikuni Nobuyuki, Shibata Tomoyuki, Arisawa Tomiyasu
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Gastroenterology
Subjects:
<it>HRH2</it>
Genetic polymorphism
Aberrant DNA methylation
Online Access:http://www.biomedcentral.com/1471-230X/13/1

Internet

http://www.biomedcentral.com/1471-230X/13/1

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