Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma

Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma

Abstract Background Chaperonin containing TCP1 subunit 3 (CCT3) acts as an oncogene in cancers, whereas its role and underlying mechanisms in lung adenocarcinoma (LUAD) are poorly understood. This study investigated the clinical relevance and function of CCT3 in LUAD. Methods Clinical relevance of C...

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Bibliographic Details
Main Authors: Kun Wang, Jian He, Changling Tu, Hui Xu, Xugang Zhang, Yongchang Lv, Chao Song
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Molecular and Cell Biology
Subjects:
LUAD
CCT3
slc7a11
Ferroptosis
AKT
Online Access:https://doi.org/10.1186/s12860-022-00424-7

Internet

https://doi.org/10.1186/s12860-022-00424-7

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