MicroRNA‐146 represses endothelial activation by inhibiting pro‐inflammatory pathways

MicroRNA‐146 represses endothelial activation by inhibiting pro‐inflammatory pathways

Abstract Activation of inflammatory pathways in the endothelium contributes to vascular diseases, including sepsis and atherosclerosis. We demonstrate that miR‐146a and miR‐146b are induced in endothelial cells upon exposure to pro‐inflammatory cytokines. Despite the rapid transcriptional induction...

Full description

Bibliographic Details
Main Authors: Henry S. Cheng, Nirojini Sivachandran, Andrew Lau, Emilie Boudreau, Jimmy L. Zhao, David Baltimore, Paul Delgado‐Olguin, Myron I. Cybulsky, Jason E. Fish
Format: Article
Language:English
Published: Springer Nature 2013-06-01
Series:EMBO Molecular Medicine
Subjects:
atherosclerosis
endothelium
gene regulation
inflammation
microRNA
Online Access:https://doi.org/10.1002/emmm.201202318

Internet

https://doi.org/10.1002/emmm.201202318

Similar Items