FLUID trial: a hospital-wide open-label cluster cross-over pragmatic comparative effectiveness randomised pilot trial comparing normal saline to Ringer’s lactate

FLUID trial: a hospital-wide open-label cluster cross-over pragmatic comparative effectiveness randomised pilot trial comparing normal saline to Ringer’s lactate

Objectives Normal saline (NS) and Ringer’s lactate (RL) are the most common crystalloids used for fluid therapy. Despite evidence of possible harm associated with NS (eg, hyperchloremic metabolic acidosis, impaired kidney function and death), few large multi-centre randomised trials have evaluated t...

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Bibliographic Details
Main Authors: John Marshall, Dean A Fergusson, Monica Taljaard, Deborah J Cook, John Muscedere, Charles Weijer, Alan J Forster, Ian D Graham, Kusum Menon, Kednapa Thavorn, Alison Fox-Robichaud, Steven Hawken, Shane W English, Claudio Martin, Andrew Seely, Ian Stiell, Tracy McArdle, Raphael Saginur, Akshai Iyengar, Colin McCartney, Lauralyn Ann McIntyre
Format: Article
Language:English
Published: BMJ Publishing Group 2023-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/2/e067142.full

Internet

https://bmjopen.bmj.com/content/13/2/e067142.full

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