A genome-wide association study of bronchodilator response in participants of European and African ancestry from six independent cohorts

A genome-wide association study of bronchodilator response in participants of European and African ancestry from six independent cohorts

Introduction Bronchodilator response (BDR) is a measurement of acute bronchodilation in response to short-acting β2-agonists, with a heritability between 10 and 40%. Identifying genetic variants associated with BDR may lead to a better understanding of its complex pathophysiology. Methods We perform...

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Bibliographic Details
Main Authors: Jessica D. Gereige, Hanfei Xu, Victor E. Ortega, Michael H. Cho, Ming Liu, Phuwanat Sakornsakolpat, Edwin K. Silverman, Terri H. Beaty, Bruce E. Miller, Per Bakke, Amund Gulsvik, Craig P. Hersh, Jarrett D. Morrow, Elizabeth J. Ampleford, Gregory A. Hawkins, Eugene R. Bleecker, Deborah A. Meyers, Stephen P. Peters, Juan C. Celedón, Kelan Tantisira, Jiang Li, Josée Dupuis, George T. O'Connor
Format: Article
Language:English
Published: European Respiratory Society 2022-06-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/8/2/00484-2021.full

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http://openres.ersjournals.com/content/8/2/00484-2021.full

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