Assessing lineage and cytolytic functional potential of murine tissue-resident innate lymphocytes

Summary: Group 1 innate lymphocytes are heterogeneous, and their ontogeny and function remain ambiguous. Here, we describe a protocol to measure cell ontogeny and effector functions of natural killer (NK) and ILC1 subsets based on current understanding of their differentiation pathways. We use cre d...

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Bibliographic Details
Main Authors: Briana G. Nixon, Chun Chou, Ming O. Li
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723000941