Gene expression and apoptosis response in hepatocellular carcinoma cells induced by biocompatible polymer/magnetic nanoparticles containing 5-fluorouracil

Gene expression and apoptosis response in hepatocellular carcinoma cells induced by biocompatible polymer/magnetic nanoparticles containing 5-fluorouracil

Background: Super-paramagnetic iron oxide nanoparticles (SPION) contain a chemotherapeutic drug and are regarded as a promising technique for improving targeted delivery into cancer cells. Results: In this study, the fabrication of 5-fluorouracil (5-FU) was investigated with loaded Dextran (DEX-SPIO...

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Bibliographic Details
Main Authors: Salih Abdul Mahdi, Afraa Ali Kadhim, Salim Albukhaty, Safoora Nikzad, Adawiya J. Haider, Sumayah Ibraheem, Haitham Ali Kadhim, Sharafaldin Al-Musawi
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Electronic Journal of Biotechnology
Subjects:
5-Fluorouracil
Apoptosis
Chemotherapeutic drug
Controlled release
Cytotoxicity
Drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345821000166

Internet

http://www.sciencedirect.com/science/article/pii/S0717345821000166

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