Neuroprotective Effects of Shenqi Fuzheng Injection in a Transgenic SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis

Neuroprotective Effects of Shenqi Fuzheng Injection in a Transgenic SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis

Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease, in the pathogenesis of which oxidative stress (OS) was believed to play a key role. Shenqi Fuzheng Injection (SFI) concocted from two kinds of Chinese medicinal herbs, Radix Codonopsis and Radix Astragali, wa...

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Bibliographic Details
Main Authors: Kazuo Sugimoto, Jia Liu, MingXuan Li, YueBo Song, Chi Zhang, ZhiGuang Zhai, Ying Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pharmacology
Subjects:
Shenqi Fuzheng Injection
amyotrophic lateral sclerosis
neurodegeneration
neuroprotective effect
oxidative stress
Nrf2 pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.701886/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.701886/full

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