Hsp70–Bag3 Module Regulates Macrophage Motility and Tumor Infiltration via Transcription Factor LITAF and CSF1

Hsp70–Bag3 Module Regulates Macrophage Motility and Tumor Infiltration via Transcription Factor LITAF and CSF1

The molecular chaperone Hsp70 has been implicated in multiple stages of cancer development. In these processes, a co-chaperone Bag3 links Hsp70 with signaling pathways that control cancer development. Recently, we showed that besides affecting cancer cells, Hsp70 can also regulate the motility of ma...

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Bibliographic Details
Main Authors: Lena Avinery, Valid Gahramanov, Arkadi Hesin, Michael Y. Sherman
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
tumor-associated macrophages
macrophage invasion
LITAF
chaperone-mediated autophagy
Online Access:https://www.mdpi.com/2072-6694/14/17/4168

Internet

https://www.mdpi.com/2072-6694/14/17/4168

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