MiR-217 regulates autophagy through OPG/RANKL/RANK in giant cell tumors

Abstract Background Increasing evidence suggests that microRNAs (miRNAs) play a crucial role in cancer development and progression. Our previous study showed remarkably lower levels of miR-217 in GCT cells and tissues, and miR-217 re-expression inhibited the occurrence and development of GCT in vitr...

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Bibliographic Details
Main Authors: Chenyang Meng, Boyong Jiang, Wanlin Liu, Lianjuan Wang, Zhenqun Zhao, Rui Bai, Yan Zhao
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-03826-1