Enhancing the Amyloid-β Anti-Aggregation Properties of Curcumin via Arene-Ruthenium(II) Derivatization

Enhancing the Amyloid-β Anti-Aggregation Properties of Curcumin via Arene-Ruthenium(II) Derivatization

Alzheimer’s disease (AD) is a fatal neurodegenerative disorder associated with severe dementia, progressive cognitive decline, and irreversible memory loss. Although its etiopathogenesis is still unclear, the aggregation of amyloid-β (Aβ) peptides into supramolecular structures and their accumulatio...

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Bibliographic Details
Main Authors: Massimiliano Cuccioloni, Valentina Cecarini, Laura Bonfili, Riccardo Pettinari, Alessia Tombesi, Noemi Pagliaricci, Laura Petetta, Mauro Angeletti, Anna Maria Eleuteri
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
amyloid-β
curcumin
organoruthenium derivative
anti-aggregating molecule
Online Access:https://www.mdpi.com/1422-0067/23/15/8710

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https://www.mdpi.com/1422-0067/23/15/8710

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