The effect of a methadone-initiated memory reconsolidation updating procedure in opioid use disorder: A translational study

Summary: Background: Opioid use disorder (OUD) is a chronic relapsing psychiatric disorder. An unconditioned stimulus (US)-triggers a memory reconsolidation updating procedure (MRUP) that has been developed and demonstrated its effectiveness in decreasing relapse to cocaine and heroin in preclinica...

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Main Authors: Jing-Li Yue, Kai Yuan, Yan-Ping Bao, Shi-Qiu Meng, Le Shi, Qing Fang, Xiao-Jie Guo, Lu Cao, Ye-Kun Sun, Tang-Sheng Lu, Na Zeng, Wei Yan, Ying Han, Jie Sun, Jie Shi, Thomas R. Kosten, Yan-Xue Xue, Ping Wu, Lin Lu
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:EBioMedicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004650