Identification of impurities in nafamostat mesylate using HPLC-IT-TOF/MS: A series of double-charged ions

Identification of impurities in nafamostat mesylate using HPLC-IT-TOF/MS: A series of double-charged ions

Nafamostat mesylate is a serine protease inhibitor used in the treatment of acute pancreatitis. The impurities in nafamostat mesylate, the active pharmaceutical ingredient (API), were profiled via high performance liquid chromatography tandem ion trap coupled with time-of-flight mass spectrometer (H...

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Bibliographic Details
Main Authors: Yuxin Zhang, Lufan An, Lin Zhang, Rulin Wang, Yuan Tian, Zunjian Zhang
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Nafamostat mesylate
Impurity
Structure identification
Double-charged ion
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177919305453

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http://www.sciencedirect.com/science/article/pii/S2095177919305453

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