Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness

Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness

COVID-19, caused by SARS-CoV-2 virus, emerged as a pandemic disease posing a severe threat to global health. To date, sporadic studies have demonstrated that innate immune mechanisms, specifically neutrophilia, NETosis, and neutrophil-associated cytokine responses, are involved in COVID-19 pathogene...

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Bibliographic Details
Main Authors: Zuzana Parackova, Irena Zentsova, Marketa Bloomfield, Petra Vrabcova, Jitka Smetanova, Adam Klocperk, Grigorij Mesežnikov, Luis Fernando Casas Mendez, Tomas Vymazal, Anna Sediva
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
COVID-19
SARS-CoV-2
neutrophils
monocytes
dendritic cells
IFN alpha
Online Access:https://www.mdpi.com/2073-4409/9/10/2206

Internet

https://www.mdpi.com/2073-4409/9/10/2206

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