Protocol for functional profiling of patient-derived organoids for precision oncology

Protocol for functional profiling of patient-derived organoids for precision oncology

Summary: Functional precision oncology—a strategy based on perturbing primary tumor cells from cancer patients—could provide a road forward for personalized treatment. Here, we present a comprehensive protocol covering generation and culture of patient-derived colorectal organoids, isolation and exp...

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Bibliographic Details
Main Authors: Niloofar Nemati, Nina Boeck, Giorgia Lamberti, Rebecca Lisandrelli, Zlatko Trajanoski
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:STAR Protocols
Subjects:
Cancer
Sequencing
RNAseq
Organoids
Systems biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724000522

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http://www.sciencedirect.com/science/article/pii/S2666166724000522

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