A Surface Exposed, Two-Domain Lipoprotein Cargo of a Type XI Secretion System Promotes Colonization of Host Intestinal Epithelia Expressing Glycans

A Surface Exposed, Two-Domain Lipoprotein Cargo of a Type XI Secretion System Promotes Colonization of Host Intestinal Epithelia Expressing Glycans

The only known required component of the newly described Type XI secretion system (TXISS) is an outer membrane protein (OMP) of the DUF560 family. TXISSOMPs are broadly distributed across proteobacteria, but properties of the cargo proteins they secrete are largely unexplored. We report biophysical,...

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Bibliographic Details
Main Authors: Alex S. Grossman, Cristian A. Escobar, Erin J. Mans, Nicholas C. Mucci, Terra J. Mauer, Katarina A. Jones, Cameron C. Moore, Paul E. Abraham, Robert L. Hettich, Liesel Schneider, Shawn R. Campagna, Katrina T. Forest, Heidi Goodrich-Blair
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
type XI secretion
symbiosis
Slam
lipidation
proteomics
metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.800366/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.800366/full

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