An inflammatory cascade leading to hyperresistinemia in humans.
Obesity, the most common cause of insulin resistance, is increasingly recognized as a low-grade inflammatory state. Adipocyte-derived resistin is a circulating protein implicated in insulin resistance in rodents, but the role of human resistin is uncertain because it is produced largely by macrophag...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2004-11-01
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Series: | PLoS Medicine |
Online Access: | http://europepmc.org/articles/PMC529430?pdf=render |