Common themes in PrP signaling: the Src remains the same
The ability of the cellular prion protein (PrPC) to trigger intracellular signals appears central to neurodegeneration pathways, yet the physiological significance of such signals is rather puzzling. For instance, PrPC deregulation disrupts phenomena as diverse as synaptic transmission in mammals an...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-10-01
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Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00063/full |