Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19
The Ig fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig fold is not just the elementary structural domain of antibodies and TCRs, it is also at the heart of a staggering 30% of immunologic cell surface receptors, making it a major orchestra...
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Format: | Article |
Language: | English |
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MDPI AG
2021-08-01
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Series: | Biomolecules |
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Online Access: | https://www.mdpi.com/2218-273X/11/9/1290 |