Transcription Factors STAT3 and MYC Are Key Players of Human Platelet Lysate-Induced Cell Proliferation

Transcription Factors STAT3 and MYC Are Key Players of Human Platelet Lysate-Induced Cell Proliferation

Human platelet lysate (HPL) is an efficient alternative for animal serum supplements, significantly enhancing stromal cell proliferation. However, the molecular mechanism behind this growth-promoting effect remains elusive. The aim of this study was to investigate the effect of HPL on cell cycle gen...

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Bibliographic Details
Main Authors: Michaela Oeller, Heidi Jaksch-Bogensperger, Markus Templin, Renate Gehwolf, Eva Rohde, Katharina Schallmoser, Sandra Laner-Plamberger
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
human platelet lysate (HPL)
signal transducer and activator of transcription 3 (STAT3)
MYC
human mesenchymal stromal cells (MSCs)
proliferation
Online Access:https://www.mdpi.com/1422-0067/23/24/15782

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https://www.mdpi.com/1422-0067/23/24/15782

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