Establishment and characterization of ovarian clear cell carcinoma patient-derived xenografts

Establishment and characterization of ovarian clear cell carcinoma patient-derived xenografts

Abstract Interest in understanding the high chemoresistance and poor prognosis of advanced ovarian clear cell carcinoma (OCCC) is rising. Patient-derived xenografts (PDX) are widely used in vivo models because of their supposedly accurate morphologic and (epi)genetic representation of patient tumors...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Joseph J. Caumanns, Shang Li, Gert J. Meersma, Evelien W. Duiker, Ate G. J. van der Zee, G. Bea A. Wisman, Steven de Jong
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Nature Portfolio 2025-02-01
Loạt:Scientific Reports
Những chủ đề:
Ovarian clear cell carcinoma
Patient derived xenografts
ARID1A
Copy number alterations
DNA methylation
Truy cập trực tuyến:https://doi.org/10.1038/s41598-025-86384-2

Internet

https://doi.org/10.1038/s41598-025-86384-2

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