A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation

The hepatopancreatic ductal (HPD) system connects both liver and pancreas to the intestine but the molecular details of HPD development are unclear. Here, the authors describe how regionalised Eph/Ephrin signaling regulates HPD morphogenesis by promoting cellular rearrangements leading to an open tu...

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Bibliographic Details
Main Authors: M. Ilcim Thestrup, Sara Caviglia, Jordi Cayuso, Ronja L. S. Heyne, Racha Ahmad, Wolfgang Hofmeister, Letizia Satriano, David G. Wilkinson, Jesper B. Andersen, Elke A. Ober
Format: Article
Language:English
Published: Nature Portfolio 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13149-7