Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells

Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells

<p>Abstract</p> <p>Background</p> <p>There is evidence that the extent of the G2/M arrest following irradiation is correlated with tumour cell survival and hence therapeutic success. We studied the regulation of cellular response to radiation treatment by miR-21-mediate...

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Bibliographic Details
Main Authors: Anastasov Nataša, Höfig Ines, Vasconcellos Iria Gonzalez, Rappl Kristina, Braselmann Herbert, Ludyga Natalie, Auer Gert, Aubele Michaela, Atkinson Michael J
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Radiation Oncology
Subjects:
MiR-21
Breast cancer
Radiation resistance
G2/M checkpoint arrest
Online Access:http://www.ro-journal.com/content/7/1/206

Internet

http://www.ro-journal.com/content/7/1/206

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